{"id":17917,"date":"2024-01-30T16:44:41","date_gmt":"2024-01-30T15:44:41","guid":{"rendered":"https:\/\/www.neo-lab.it\/cose-circomp\/"},"modified":"2025-01-22T15:23:45","modified_gmt":"2025-01-22T14:23:45","slug":"clinical-research","status":"publish","type":"page","link":"https:\/\/www.neo-lab.it\/en\/clinical-research\/","title":{"rendered":"Clinical research"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"17917\" class=\"elementor elementor-17917 elementor-16519\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8f5d4dc e-con-full e-flex e-con e-parent\" data-id=\"8f5d4dc\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b221cf5 elementor-widget elementor-widget-shortcode\" data-id=\"b221cf5\" data-element_type=\"widget\" data-widget_type=\"shortcode.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-shortcode\">\t\t<div data-elementor-type=\"section\" data-elementor-id=\"18117\" class=\"elementor elementor-18117 elementor-16543\" data-elementor-post-type=\"elementor_library\">\n\t\t\t<div class=\"elementor-element elementor-element-c6db7df e-flex e-con-boxed e-con e-parent\" data-id=\"c6db7df\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-00a1989 e-con-full e-flex e-con e-child\" data-id=\"00a1989\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\n <\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e511a62 e-con-full e-flex e-con e-parent\" data-id=\"e511a62\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-61f8d22 e-con-full e-flex e-con e-child\" data-id=\"61f8d22\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-49d4d39 elementor-widget elementor-widget-heading\" data-id=\"49d4d39\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Neonatal bone health<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-34076c3 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"34076c3\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fa6c210 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"fa6c210\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"p1\">Bone health represents another cornerstone of our clinical research. We investigate the factors influencing bone development in newborns, aiming to establish baseline values for mineralization and bone mineral density across various newborn populations. These findings can offer critical insights into the potential risk of osteopenia and\/or osteoporosis.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a75238d e-con-full e-flex e-con e-child\" data-id=\"a75238d\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6396289 elementor-hidden-widescreen elementor-hidden-desktop elementor-hidden-laptop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"6396289\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-aa3aa7f elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"aa3aa7f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">The role of the olfactory system in the study of neonatal neurodevelopment<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4105c11 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"4105c11\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bbf7b6a elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"bbf7b6a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"p1\">Another central theme of our research is the <span class=\"s1\"><b>study of the olfactory system in the infant with signs of asphyxia at birth.<\/b><\/span>, a unique window into neurodevelopment in infants. We analyze how the sense of smell may provide insight into neurobehavioral status and early brain connections, with the goal of using this knowledge to identify potential future markers of atypical development. <\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4db8671 elementor-hidden-widescreen elementor-hidden-desktop elementor-hidden-laptop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"4db8671\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c059888 e-con-full e-flex e-con e-child\" data-id=\"c059888\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4b25ed8 elementor-widget elementor-widget-heading\" data-id=\"4b25ed8\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Monitoring of the autonomic nervous system in infants<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fc55f4e elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"fc55f4e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>We also devote considerable attention to the <strong>autonomic nervous system<\/strong>, exploring how it regulates vital functions in infants, including heart rate variability (HRV) and cortisol levels. Through analysis of various autonomic and neuroendocrine system indices, we seek to develop tools to monitor homeostasis and detect early signs of dysfunction, especially in infants subjected to &#8216;stressors&#8217; during pregnancy, such as maternal hyperglycemia given by Gestational Diabetes Mellitus or with severe infections. <\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5b0e95d e-con-full e-flex e-con e-child\" data-id=\"5b0e95d\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ea86fc1 e-flex e-con-boxed e-con e-parent\" data-id=\"ea86fc1\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-db8b2b1 e-con-full e-flex e-con e-child\" data-id=\"db8b2b1\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-76aee08 elementor-widget elementor-widget-heading\" data-id=\"76aee08\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Biomarkers and neuroprotective strategies<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d7c094f elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"d7c094f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"p1\">Our clinical research is centered on key areas of neonatology, tackling critical challenges with cutting-edge approaches. One of our primary clinical research focuses is on <strong>biomarkers of oxidative stress<\/strong>, which serve as essential tools for the early detection of infants at risk of brain injury. Through these studies, we aim to develop innovative neuroprotective strategies and therapies to prevent or mitigate brain injuries, thereby enhancing long-term developmental outcomes.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f1ebaea e-con-full e-flex e-con e-child\" data-id=\"f1ebaea\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c6f92c7 e-flex e-con-boxed e-con e-parent\" data-id=\"c6f92c7\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-3946bde e-con-full e-flex e-con e-child\" data-id=\"3946bde\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-661aa13 elementor-widget elementor-widget-heading\" data-id=\"661aa13\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Integrated clinical research for early intervention<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7520c45 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"7520c45\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"p1\">Finally, through an integrated and multidisciplinary approach, we investigate the interactions between genetic, environmental, and clinical factors, striving to develop early and personalized interventions. Our mission is to translate these scientific discoveries into clinical practices that enhance neonatal care and foster healthy, harmonious growth.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f8bbf5d e-con-full e-flex e-con e-child\" data-id=\"f8bbf5d\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Neonatal bone health Bone health represents another cornerstone of our clinical research. We investigate the factors influencing bone development in newborns, aiming to establish baseline values for mineralization and bone mineral density across various newborn populations. These findings can offer critical insights into the potential risk of osteopenia and\/or osteoporosis. 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